Mechanically-driven stem cell separation in tissues caused by proliferating daughter cells
The homeostasis of epithelial tissue relies on a balance between the self-renewal of stem cell populations, cellular differentiation, and loss. Although this balance needs to be tightly regulated to avoid pathologies, such as tumor growth, the regulatory mechanisms, both cell-intrinsic and collectiv...
| Main Author: | |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
SciPost
2024-04-01
|
| Series: | SciPost Physics |
| Online Access: | https://scipost.org/SciPostPhys.16.4.097 |