Metformin attenuates inflammation and boosts autophagy in the liver and intestine of chronologically aged rats

Background: Our previous studies found that autophagy levels in liver and intestinal segments of naturally aging rats were downregulated, and the expression of pro-inflammatory factors was increased. The increased expression of pro-inflammatory factors might be related to the downregulation of autop...

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Bibliographic Details
Main Authors: Zheng Kuai, Xin Chao, Yuting He, Weiying Ren
Format: Article
Language:English
Published: Elsevier 2023-12-01
Series:Experimental Gerontology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0531556523002528