Modelling membrane reshaping by staged polymerization of ESCRT-III filaments.

ESCRT-III filaments are composite cytoskeletal polymers that can constrict and cut cell membranes from the inside of the membrane neck. Membrane-bound ESCRT-III filaments undergo a series of dramatic composition and geometry changes in the presence of an ATP-consuming Vps4 enzyme, which causes stepw...

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Bibliographic Details
Main Authors: Xiuyun Jiang, Lena Harker-Kirschneck, Christian Vanhille-Campos, Anna-Katharina Pfitzner, Elene Lominadze, Aurélien Roux, Buzz Baum, Anđela Šarić
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-10-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1010586