Chromatin Trapping of Factors Involved in DNA Replication and Repair Underlies Heat-Induced Radio- and Chemosensitization

Chromatin Trapping of Factors Involved in DNA Replication and Repair Underlies Heat-Induced Radio- and Chemosensitization

Hyperthermia has been used as an adjuvant treatment for radio- and chemotherapy for decades. In addition to its effects on perfusion and oxygenation of cancer tissues, hyperthermia can enhance the efficacy of DNA-damaging treatments such as radiotherapy and chemotherapy. Although it is believed that...

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Bibliographic Details
Main Authors: Artem V. Luzhin, Bogdan Avanesyan, Artem K. Velichko, Victoria O. Shender, Natalia Ovsyannikova, Georgij P. Arapidi, Polina V. Shnaider, Nadezhda V. Petrova, Igor I. Kireev, Sergey V. Razin, Omar L. Kantidze
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Cells
Subjects:
hyperthermia
DNA repair
DNA replication
chromatin
PARP
Online Access:https://www.mdpi.com/2073-4409/9/6/1423

Internet

https://www.mdpi.com/2073-4409/9/6/1423

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