Synthesis and Structural Analysis of Chiral Bis-dihydro[1,3]-naphthoxazines and Imidazolidine Derivatives Prepared by Three-Component Mannich-Type Condensation

Synthesis and Structural Analysis of Chiral Bis-dihydro[1,3]-naphthoxazines and Imidazolidine Derivatives Prepared by Three-Component Mannich-Type Condensation

Enantiomerically pure (<i>S</i>)-1-phenylethan-1-amine has been applied in Mannich-type condensation between formaldehyde and naphthalenediols leading to the synthesis of chiral bis-dihydro[1,3]naphthoxazines in excellent yields. Salen-type structures have been synthesized, applying <...

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Bibliographic Details
Main Authors: Maya Tavlinova-Kirilova, Krasimira Dikova, Maya K. Marinova, Mariana Kamenova-Nacheva, Rusi Rusew, Hristina Sbirkova-Dimitrova, Boris Shivachev, Kalina Kostova, Vladimir Dimitrov
Format: Article
Language:English
Published: MDPI AG 2023-10-01
Series:Crystals
Subjects:
Mannich condensation
bis-dihydro[1,3]naphthoxazines
<i>R</i>,<i>R</i>- or <i>S</i>,<i>S</i>-cyclohexane-1,2-diamine
chiral ligand
enantioselectivity
X-ray crystallography
Online Access:https://www.mdpi.com/2073-4352/13/10/1495

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https://www.mdpi.com/2073-4352/13/10/1495

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