Construction and Experimental Validation of a Petri Net Model of Wnt/β-Catenin Signaling.

The Wnt/β-catenin signaling pathway is important for multiple developmental processes and tissue maintenance in adults. Consequently, deregulated signaling is involved in a range of human diseases including cancer and developmental defects. A better understanding of the intricate regulatory mechanis...

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Bibliographic Details
Main Authors: Annika Jacobsen, Nika Heijmans, Folkert Verkaar, Martine J Smit, Jaap Heringa, Renée van Amerongen, K Anton Feenstra
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4878796?pdf=render