Long Non-coding RNA IRAIN Inhibits VEGFA Expression via Enhancing Its DNA Methylation Leading to Tumor Suppression in Renal Carcinoma

Long Non-coding RNA IRAIN Inhibits VEGFA Expression via Enhancing Its DNA Methylation Leading to Tumor Suppression in Renal Carcinoma

Aims: Long non-coding RNA IRAIN (lncRNA IRAIN) plays a critical role in numerous malignancies. However, the function of lncRNA IRAIN in renal carcinoma (RC) remains enigmatic. The purpose of this study is to characterize the effects of lncRNA IRAIN on RC progression.Methods: The expression pattern o...

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Bibliographic Details
Main Authors: Yang Li, Qingyang Luo, Zun Li, Yun Wang, Chaoyang Zhu, Tieqiang Li, Xiaodong Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-09-01
Series:Frontiers in Oncology
Subjects:
renal carcinoma
long non-coding RNA IRAIN
vascular endothelial growth factor A
DNA methyltransferase
DNA methylation
tumor-suppressive potential
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2020.01082/full

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https://www.frontiersin.org/article/10.3389/fonc.2020.01082/full

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