Hierarchical Bayesian inference for ion channel screening dose-response data [version 2; referees: 2 approved]

Dose-response (or ‘concentration-effect’) relationships commonly occur in biological and pharmacological systems and are well characterised by Hill curves. These curves are described by an equation with two parameters: the inhibitory concentration 50% (IC50); and the Hill coefficient. Typically just...

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Bibliographic Details
Main Authors: Ross H Johnstone, Rémi Bardenet, David J Gavaghan, Gary R Mirams
Format: Article
Language:English
Published: Wellcome 2017-03-01
Series:Wellcome Open Research
Subjects:
Online Access:https://wellcomeopenresearch.org/articles/1-6/v2