A new, potent and placenta-permeable macrolide antibiotic, solithromycin, for the prevention and treatment of bacterial infections in pregnancy

Intrauterine infection-inflammation is a major cause of early preterm birth and subsequent neonatal morbidity and acute or long-term mortality. Antibiotics can be administered in pregnancy to prevent preterm birth either prophylactically to women at high risk for preterm delivery, or to women with d...

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Bibliographic Details
Main Authors: Jeffrey A Keelan, Matthew S Payne, Matthew eKemp, Demelza Jane Ireland, John Phillipps Newnham
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-04-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2016.00111/full