Study on the effect and mechanism of Pirfenidone on endothelial-mesenchymal transition in endothelial cells

Study on the effect and mechanism of Pirfenidone on endothelial-mesenchymal transition in endothelial cells

AIM:To establish the hypoxia induced endothelial-mesenchymal transition(EndoMT)model of endothelial cells, and to investigate the effect and mechanism of Pirfenidone(PFD)on inhibiting the subretinal fibrosis progression.METHODS: Primary cultured human umbilical vein endothelial cells(HUVEC), 4-7 pas...

Full description

Bibliographic Details
Main Authors: Ding-Ying Liao, Li-Li Fu, Yu-Ping Zheng, Li-Jun Wang, Hong-Song Li, Wen-Yi Zhang, Jian-Ming Wang, Lin Zhao
Format: Article
Language:English
Published: Press of International Journal of Ophthalmology (IJO PRESS) 2021-02-01
Series:Guoji Yanke Zazhi
Subjects:
pirfenidone
endothelial cell
endothelial-mesenchymal transition
subretinal fibrosis
Online Access:http://ies.ijo.cn/cn_publish/2021/2/202102003.pdf

Internet

http://ies.ijo.cn/cn_publish/2021/2/202102003.pdf

Similar Items