The dynamic expression of YAP is essential for the development of male germ cells derived from human embryonic stem cells

The dynamic expression of YAP is essential for the development of male germ cells derived from human embryonic stem cells

Abstract YAP plays a vital role in controlling growth and differentiation in various cell lineages. Although the expression of YAP in mice testicular and spermatogenic cells suggests its role in mammalian spermatogenesis, the role of YAP in the development of human male germ cells has not yet been d...

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Bibliographic Details
Main Authors: Sujittra Khampang, Chanchao Lorthongpanich, Chuti Laowtammathron, Phatchanat Klaihmon, Sukanya Meesa, Wichuda Suksomboon, Nittaya Jiamvoraphong, Pakpoom Kheolamai, Sudjit Luanpitpong, Charles A. Easley, Eisa Mahyari, Surapol Issaragrisil
Format: Article
Language:English
Published: Nature Portfolio 2024-07-01
Series:Scientific Reports
Subjects:
YAP
Hippo signaling pathway
Spermatogonia stem cells
Spermatogenic cell differentiation
Human embryonic stem cells
Online Access:https://doi.org/10.1038/s41598-024-66852-x

Internet

https://doi.org/10.1038/s41598-024-66852-x

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