Structural insights into substrate recognition by the type VII secretion system

Abstract Type VII secretion systems (T7SSs) are found in many disease related bacteria including Mycobacterium tuberculosis (Mtb). ESX-1 [early secreted antigen 6 kilodaltons (ESAT-6) system 1] is one of the five subtypes (ESX-1~5) of T7SSs in Mtb, where it delivers virulence factors into host macro...

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Bibliographic Details
Main Authors: Shuhui Wang, Kaixuan Zhou, Xiaolin Yang, Bing Zhang, Yao Zhao, Yu Xiao, Xiuna Yang, Haitao Yang, Luke W. Guddat, Jun Li, Zihe Rao
Format: Article
Language:English
Published: Oxford University Press 2019-11-01
Series:Protein & Cell
Subjects:
Online Access:http://link.springer.com/article/10.1007/s13238-019-00671-z