Infiltration of Apoptotic M2 Macrophage Subpopulation Is Negatively Correlated with the Immunotherapy Response in Colorectal Cancer

Infiltration of Apoptotic M2 Macrophage Subpopulation Is Negatively Correlated with the Immunotherapy Response in Colorectal Cancer

The polarization of tumor-associated macrophages (TAMs) plays a key role in tumor development and immunotherapy in colorectal cancer (CRC) patients. However, the impact of apoptosis on TAM polarization and immunotherapy efficacy in patients with different mismatch repair statuses (MMR) remains uncle...

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Bibliographic Details
Main Authors: Rui Liu, Chongyin Han, Jiaqi Hu, Baowen Zhang, Wei Luo, Fei Ling
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:International Journal of Molecular Sciences
Subjects:
colorectal cancer
tumor-associated macrophages
polarization
apoptosis
S100A6
immunotherapy
Online Access:https://www.mdpi.com/1422-0067/23/19/11014

Internet

https://www.mdpi.com/1422-0067/23/19/11014

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