The Anti-Atherosclerotic Action of FFAR4 Agonist TUG-891 in ApoE–Knockout Mice Is Associated with Increased Macrophage Polarization towards M2 Phenotype

<b>Background:</b> Over the past few years, a better understanding of the biology of G-protein coupled receptors (GPRs) has led to the identification of several receptors as novel targets for free fatty acids (FFAs). FFAR4 has received special attention in the context of chronic inflamma...

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Main Authors: Anna Kiepura, Kamila Stachyra, Anna Wiśniewska, Katarzyna Kuś, Klaudia Czepiel, Maciej Suski, Magdalena Ulatowska-Białas, Marcin Surmiak, Rafał Olszanecki
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/22/18/9772