Rapid in situ carbon-13 hyperpolarization and imaging of acetate and pyruvate esters without external polarizer

Rapid in situ carbon-13 hyperpolarization and imaging of acetate and pyruvate esters without external polarizer

Abstract Hyperpolarized 13C MRI visualizes real-time metabolic processes in vivo. In this study, we achieved high 13C polarization in situ in the bore of an MRI system for precursor molecules of most widely employed hyperpolarized agents: [1-13C]acetate and [1-13C]pyruvate ethyl esters in their perd...

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Main Authors: Obaid Mohiuddin, Henri de Maissin, Andrey N. Pravdivtsev, Arne Brahms, Marvin Herzog, Leif Schröder, Eduard Y. Chekmenev, Rainer Herges, Jan-Bernd Hövener, Maxim Zaitsev, Dominik von Elverfeldt, Andreas B. Schmidt
Format: Article
Language:English
Published: Nature Portfolio 2024-10-01
Series:Communications Chemistry
Online Access:https://doi.org/10.1038/s42004-024-01316-x

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https://doi.org/10.1038/s42004-024-01316-x

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