DNMT1-induced miR-378a-3p silencing promotes angiogenesis via the NF-κB signaling pathway by targeting TRAF1 in hepatocellular carcinoma

DNMT1-induced miR-378a-3p silencing promotes angiogenesis via the NF-κB signaling pathway by targeting TRAF1 in hepatocellular carcinoma

Abstract Background Angiogenesis plays an important role in the occurrence, development and metastasis of hepatocellular carcinoma (HCC). According to previous studies, miR-378a participates in tumorigenesis and tumor metastasis, but its exact role in HCC angiogenesis remains poorly understood. Meth...

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Bibliographic Details
Main Authors: Bin Zhu, Jun-Jie Chen, Ying Feng, Jun-Ling Yang, Hua Huang, Wen Yuan Chung, Yi-Lin Hu, Wan-Jiang Xue
Format: Article
Language:English
Published: BMC 2021-11-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Angiogenesis
HCC
miR-378a-3p
TRAF1
DNA methylation
Online Access:https://doi.org/10.1186/s13046-021-02110-6

Internet

https://doi.org/10.1186/s13046-021-02110-6

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