Simultaneous effect of different chromatographic conditions on the chromatographic retention of pentapeptide derivatives (HGRFG and NPNPT)

Simultaneous effect of different chromatographic conditions on the chromatographic retention of pentapeptide derivatives (HGRFG and NPNPT)

Introduction: Oligopeptides exhibit great prospects for clinical application and its separation is of great importance in new drug development.Methods: To accurately predict the retention of pentapeptides with analogous structures in chromatography, the retention times of 57 pentapeptide derivatives...

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Bibliographic Details
Main Authors: Huan Peng, Xiangrong Yang, Huanle Fang, Zhongqi Zhang, Jinli Zhao, Te Zhao, Jianli Liu, Yan Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-04-01
Series:Frontiers in Chemistry
Subjects:
chromatographic retention
pentapeptides
six-parameter model
retention factor
prediction capacity
Online Access:https://www.frontiersin.org/articles/10.3389/fchem.2023.1171824/full

Internet

https://www.frontiersin.org/articles/10.3389/fchem.2023.1171824/full

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