Revealing Inflammatory Indications Induced by Titanium Alloy Wear Debris in Periprosthetic Tissue by Label-Free Correlative High-Resolution Ion, Electron and Optical Microspectroscopy

Revealing Inflammatory Indications Induced by Titanium Alloy Wear Debris in Periprosthetic Tissue by Label-Free Correlative High-Resolution Ion, Electron and Optical Microspectroscopy

The metallic-associated adverse local tissue reactions (ALTR) and events accompanying worn-broken implant materials are still poorly understood on the subcellular and molecular level. Current immunohistochemical techniques lack spatial resolution and chemical sensitivity to investigate causal relati...

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Bibliographic Details
Main Authors: Rok Podlipec, Esther Punzón-Quijorna, Luka Pirker, Mitja Kelemen, Primož Vavpetič, Rajko Kavalar, Gregor Hlawacek, Janez Štrancar, Primož Pelicon, Samo K. Fokter
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Materials
Subjects:
adverse local tissue reactions (ALTR)
total hip arthroplasty (THA)
titanium alloy
wear debris
periprosthetic tissue
correlative microscopy
Online Access:https://www.mdpi.com/1996-1944/14/11/3048

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https://www.mdpi.com/1996-1944/14/11/3048

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