Renewable Human Cell Model for Type 1 Diabetes Research: EndoC-βH5/HUVEC Coculture Spheroids

In vitro drug screening for type 1 diabetes therapies has largely been conducted on human organ donor islets for proof of efficacy. While native islets are the ultimate target of these drugs (either in situ or for transplantation), significant benefit can be difficult to ascertain due to the highly...

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Bibliographic Details
Main Authors: James M. Porter, Michael Yitayew, Maryam Tabrizian
Format: Article
Language:English
Published: Hindawi Limited 2023-01-01
Series:Journal of Diabetes Research
Online Access:http://dx.doi.org/10.1155/2023/6610007