Depletion of gut microbiota induces skeletal muscle atrophy by FXR-FGF15/19 signalling

Depletion of gut microbiota induces skeletal muscle atrophy by FXR-FGF15/19 signalling

AbstractBackground: Recent evidence indicates that host-gut microbiota crosstalk has nonnegligible effects on host skeletal muscle, yet gut microbiota-regulating mechanisms remain obscure.Methods: C57BL/6 mice were treated with a cocktail of antibiotics (Abx) to depress gut microbiota for 4 weeks. T...

Full description

Bibliographic Details
Main Authors: Yixuan Qiu, Jiaming Yu, Yi Li, Fan Yang, Huiyuan Yu, Mengjuan Xue, Fan Zhang, Xin Jiang, Xueying Ji, Zhijun Bao
Format: Article
Language:English
Published: Taylor & Francis Group 2021-01-01
Series:Annals of Medicine
Subjects:
Gut microbiota
skeletal muscle
bile acid
FXR
FGF15/19
Online Access:https://www.tandfonline.com/doi/10.1080/07853890.2021.1900593

Internet

https://www.tandfonline.com/doi/10.1080/07853890.2021.1900593

Similar Items