Development of a universal, oriented antibody immobilization method to functionalize vascular prostheses for enhanced endothelialization for potential clinical application

Development of a universal, oriented antibody immobilization method to functionalize vascular prostheses for enhanced endothelialization for potential clinical application

Abstract Background Thrombosis is a common cause of vascular prosthesis failure. Antibody coating of prostheses to capture circulating endothelial progenitor cells to aid endothelialization on the device surface appears a promising solution to prevent thrombus formation. Compared with random antibod...

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Bibliographic Details
Main Authors: Qiuwang Zhang, Sebastian Duncan, Daniel A. Szulc, Charles de Mestral, Michael JB Kutryk
Format: Article
Language:English
Published: BMC 2023-06-01
Series:Journal of Biological Engineering
Subjects:
Cardiovascular prosthetic device
Thrombosis
Endothelial progenitor cells
Oriented antibody immobilization
Universal coating
Clinical application
Online Access:https://doi.org/10.1186/s13036-023-00356-6

Internet

https://doi.org/10.1186/s13036-023-00356-6

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