Validation of Candidate Host Cell Entry Factors for Bovine Herpes Virus Type-1 Based on a Genome-Wide CRISPR Knockout Screen

Validation of Candidate Host Cell Entry Factors for Bovine Herpes Virus Type-1 Based on a Genome-Wide CRISPR Knockout Screen

To identify host factors that affect Bovine Herpes Virus Type 1 (BoHV-1) infection we previously applied a genome wide CRISPR knockout screen targeting all bovine protein coding genes. By doing so we compiled a list of both pro-viral and anti-viral proteins involved in BoHV-1 replication. Here we pr...

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Bibliographic Details
Main Authors: Wenfang Spring Tan, Enguang Rong, Inga Dry, Simon Lillico, Andy Law, Paul Digard, Bruce Whitelaw, Robert G. Dalziel
Format: Article
Language:English
Published: MDPI AG 2024-02-01
Series:Viruses
Subjects:
CRISPR/Cas9
BoHV-1
cell entry
receptors
heparan Sulfate
Golgi apparatus
Online Access:https://www.mdpi.com/1999-4915/16/2/297

Internet

https://www.mdpi.com/1999-4915/16/2/297

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