Beta-1,4-galactosyltransferase-3 deficiency suppresses the growth of immunogenic tumors in mice

Beta-1,4-galactosyltransferase-3 deficiency suppresses the growth of immunogenic tumors in mice

BackgroundBeta-1,4-galactosyltransferase-3 (B4GALT3) belongs to the family of beta-1,4-galactosyltransferases (B4GALTs) and is responsible for the transfer of UDP-galactose to terminal N-acetylglucosamine. B4GALT3 is differentially expressed in tumors and adjacent normal tissues, and is correlated w...

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Bibliographic Details
Main Authors: Heng Wei, Chie Naruse, Daisuke Takakura, Kazushi Sugihara, Xuchi Pan, Aki Ikeda, Nana Kawasaki, Masahide Asano
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-10-01
Series:Frontiers in Immunology
Subjects:
galactosyltransferase
tumor immune microenvironment
N-glycosylation
glycoproteomics
immunogenicity
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1272537/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1272537/full

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