Anti-inflammatory and antioxidant activities of methanol extract of Piper betle Linn. (Piper betle L.) leaves and stems by inhibiting NF-κB/MAPK/Nrf2 signaling pathways in RAW 264.7 macrophages

Anti-inflammatory and antioxidant activities of methanol extract of Piper betle Linn. (Piper betle L.) leaves and stems by inhibiting NF-κB/MAPK/Nrf2 signaling pathways in RAW 264.7 macrophages

Oxidative stress and chronic inflammation are closely linked to various diseases. However, previous studies have demonstrated that plant extracts could prevent and alleviate these adverse outcomes. Piper betle Linn. (Piper betle L.) is a cosmopolitan plant that belongs to the Piperaceae family, whos...

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Bibliographic Details
Main Authors: Jihye Seo, Unju Lee, Sumin Seo, Agung Eru Wibowo, Olivia Bunga Pongtuluran, KyuJong Lee, Sang Beom Han, Sayeon Cho
Format: Article
Language:English
Published: Elsevier 2022-11-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Piper betle L. leaves and stems
Anti-inflammatory activity
Antioxidant activity
NF-κB pathway
MAPK pathway
Nrf2 pathway
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332222011234

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http://www.sciencedirect.com/science/article/pii/S0753332222011234

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