A random effects model for the identification of differential splicing (REIDS) using exon and HTA arrays

A random effects model for the identification of differential splicing (REIDS) using exon and HTA arrays

Abstract Background Alternative gene splicing is a common phenomenon in which a single gene gives rise to multiple transcript isoforms. The process is strictly guided and involves a multitude of proteins and regulatory complexes. Unfortunately, aberrant splicing events do occur which have been linke...

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Bibliographic Details
Main Authors: Marijke Van Moerbeke, Adetayo Kasim, Willem Talloen, Joke Reumers, Hinrick W. H. Göhlmann, Ziv Shkedy
Format: Article
Language:English
Published: BMC 2017-05-01
Series:BMC Bioinformatics
Subjects:
Exon arrays
HTA arrays
Alternative splicing
Mixed effects models
Online Access:http://link.springer.com/article/10.1186/s12859-017-1687-8

Internet

http://link.springer.com/article/10.1186/s12859-017-1687-8

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