An in vitro cytotoxicity of glufosfamide in HepG2 cells relative to its nonconjugated counterpart
Abstract Background Glufosfamide (β-d-glucosylisophosphoramide mustard, GLU) is an alkylating cytotoxic agent in which ifosforamide mustard (IPM) is glycosidically linked to the β-d-glucose molecule. GLU exerted its cytotoxic effect as a targeted chemotherapy. Although, its cytotoxic efficacy in a n...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
SpringerOpen
2021-08-01
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Series: | Journal of the Egyptian National Cancer Institute |
Subjects: | |
Online Access: | https://doi.org/10.1186/s43046-021-00080-6 |