Peptidoglycan-associated lipoprotein of Aggregatibacter actinomycetemcomitans induces apoptosis and production of proinflammatory cytokines via TLR2 in murine macrophages RAW 264.7 in vitro

Peptidoglycan-associated lipoprotein of Aggregatibacter actinomycetemcomitans induces apoptosis and production of proinflammatory cytokines via TLR2 in murine macrophages RAW 264.7 in vitro

Peptidoglycan-associated lipoprotein (PAL) is a conserved pro-inflammatory outer membrane lipoprotein in Gram-negative bacteria. Compared to systemic pathogens, little is known about the virulence properties of PAL in Aggregatibacter actinomycetemcomitans (AaPAL). The aims of this study were to inve...

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Bibliographic Details
Main Authors: Riikka Ihalin, Kjell Eneslätt, Sirkka Asikainen
Format: Article
Language:English
Published: Taylor & Francis Group 2018-01-01
Series:Journal of Oral Microbiology
Subjects:
Aggregatibacter actinomycetemcomitans
apoptosis
mouse macrophages
pro-inflammatory cytokines
peptidoglycan-associated lipoprotein
Online Access:http://dx.doi.org/10.1080/20002297.2018.1442079

Internet

http://dx.doi.org/10.1080/20002297.2018.1442079

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