Synergistic combinations of novel polymyxins and rifampicin with improved eradication of colistin-resistant Pseudomonas aeruginosa biofilms

Background: Increased prevalence of antimicrobial resistance coupled with a lack of new antibiotics against Gram-negative bacteria emphasize the imperative for novel therapeutic strategies. Colistin-resistant Pseudomonas aeruginosa constitutes a challenge, where conventional treatment options lack e...

Full description

Bibliographic Details
Main Authors: Johan Storm Jørgensen, Anne Sofie Laulund Siebert, Oana Ciofu, Niels Høiby, Claus Moser, Henrik Franzyk
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Biofilm
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2590207524000492