Metabolic Enzyme SLC27A5 Regulates PIP4K2A pre‐mRNA Splicing as a Noncanonical Mechanism to Suppress Hepatocellular Carcinoma Metastasis

Metabolic Enzyme SLC27A5 Regulates PIP4K2A pre‐mRNA Splicing as a Noncanonical Mechanism to Suppress Hepatocellular Carcinoma Metastasis

Abstract Solute carrier family 27 member 5, a key enzyme in fatty acid transport and bile acid metabolism in the liver, is frequently expressed in low quantities in patients with hepatocellular carcinoma, resulting in poor prognosis. However, it is unclear whether SLC27A5 plays non‐canonical functio...

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Bibliographic Details
Main Authors: Dan Nie, Xin Tang, Haijun Deng, Xiaojun Yang, Junji Tao, Fengli Xu, Yi Liu, Kang Wu, Kai Wang, Zhechuan Mei, Ailong Huang, Ni Tang
Format: Article
Language:English
Published: Wiley 2024-02-01
Series:Advanced Science
Subjects:
alternative splicing
HCC
nonmetabolic functions
PIP4K2A‐S, SLC27A5
Online Access:https://doi.org/10.1002/advs.202305374

Internet

https://doi.org/10.1002/advs.202305374

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