Staphylococcus aureus alpha-hemolysin activates the NLRP3-inflammasome in human and mouse monocytic cells.

Staphylococcus aureus alpha-hemolysin activates the NLRP3-inflammasome in human and mouse monocytic cells.

Community Acquired Methicillin Resistant Staphylococcus aureus (CA-MRSA) causes severe necrotizing infections of the skin, soft tissues, and lungs. Staphylococcal alpha-hemolysin is an essential virulence factor in mouse models of CA-MRSA necrotizing pneumonia. S. aureus alpha-hemolysin has long bee...

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Bibliographic Details
Main Authors: Robin R Craven, Xi Gao, Irving C Allen, Denis Gris, Juliane Bubeck Wardenburg, Erin McElvania-Tekippe, Jenny P Ting, Joseph A Duncan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-10-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2758589?pdf=render

Internet

http://europepmc.org/articles/PMC2758589?pdf=render

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