Functional Granulocyte–Macrophage Colony-Stimulating Factor (GM-CSF) Delivered by Canine Histiocytic Sarcoma Cells Persistently Infected with Engineered Attenuated Canine Distemper Virus

Functional Granulocyte–Macrophage Colony-Stimulating Factor (GM-CSF) Delivered by Canine Histiocytic Sarcoma Cells Persistently Infected with Engineered Attenuated Canine Distemper Virus

The immune response plays a key role in the treatment of malignant tumors. One important molecule promoting humoral and cellular immunity is granulocyte–macrophage colony-stimulating factor (GM-CSF). Numerous successful trials have led to the approval of this immune-stimulating molecule for cancer t...

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Bibliographic Details
Main Authors: Katarzyna Marek, Federico Armando, Thanaporn Asawapattanakul, Vanessa Maria Nippold, Philippe Plattet, Gisa Gerold, Wolfgang Baumgärtner, Christina Puff
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:Pathogens
Subjects:
canine distemper virus
DH82 cells
genetically engineered viruses
GM-CSF
histiocytic sarcoma
viral oncolysis
Online Access:https://www.mdpi.com/2076-0817/12/7/877

Internet

https://www.mdpi.com/2076-0817/12/7/877

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