Stabilization of Poly (β-Amino Ester) Nanoparticles for the Efficient Intracellular Delivery of PiggyBac Transposon

The administration of gene-editing tools has been proposed as a promising therapeutic approach for correcting mutations that cause diseases. Gene-editing tools, composed of relatively large plasmid DNA constructs that often need to be co-delivered with a guiding protein, are unable to spontaneously...

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Bibliographic Details
Main Authors: Tina Rodgers, Nicolas Muzzio, Caleb Watson, Gabriela Romero
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Bioengineering
Subjects:
Online Access:https://www.mdpi.com/2306-5354/8/2/16