Radiation-induced non-targeted effect of immunity provoked by mitochondrial DNA damage triggered cGAS/ AIM2 pathways

Non-targeted effect is an important complement to the classical target theory of radiation biology which takes nuclear genomic DNA as the core target. The principle of radiation target theory is to assume that an organism or cell has one or more sensitive points or targets, hit and inactivation of w...

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Bibliographic Details
Main Authors: Wen Zhang, Shi Chen, Hua Guan, Ping-Kun Zhou
Format: Article
Language:English
Published: Elsevier 2022-06-01
Series:Radiation Medicine and Protection
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2666555722000260