Intrathecal CAR-NK cells infusion for isolated CNS relapse after allogeneic stem cell transplantation: case report

Intrathecal CAR-NK cells infusion for isolated CNS relapse after allogeneic stem cell transplantation: case report

Abstract A 24-year-old man with central nervous system (CNS) involvement of T-cell lineage acute lymphoblastic leukemia received sibling allogeneic stem cell transplantation (allo-SCT). He developed isolated CNS relapse early post-SCT, while high-dose systemic chemotherapy, intrathecal (IT) triple i...

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Bibliographic Details
Main Authors: Jing Yuan, Fuxu Wang, Hanyun Ren
Format: Article
Language:English
Published: BMC 2023-03-01
Series:Stem Cell Research & Therapy
Subjects:
CAR-NK cells
Intrathecal infusion
CNS relapse
Allogeneic stem cell transplantation
Case report
Online Access:https://doi.org/10.1186/s13287-023-03272-0

Internet

https://doi.org/10.1186/s13287-023-03272-0

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