Intrathecal CAR-NK cells infusion for isolated CNS relapse after allogeneic stem cell transplantation: case report

Intrathecal CAR-NK cells infusion for isolated CNS relapse after allogeneic stem cell transplantation: case report

Abstract A 24-year-old man with central nervous system (CNS) involvement of T-cell lineage acute lymphoblastic leukemia received sibling allogeneic stem cell transplantation (allo-SCT). He developed isolated CNS relapse early post-SCT, while high-dose systemic chemotherapy, intrathecal (IT) triple i...

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Bibliographic Details
Main Authors:	Jing Yuan, Fuxu Wang, Hanyun Ren
Format:	Article
Language:	English
Published:	BMC 2023-03-01
Series:	Stem Cell Research & Therapy
Subjects:	CAR-NK cells Intrathecal infusion CNS relapse Allogeneic stem cell transplantation Case report
Online Access:	https://doi.org/10.1186/s13287-023-03272-0

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