Integrative analysis of transcriptional regulatory network and copy number variation in intrahepatic cholangiocarcinoma.

BACKGROUND: Transcriptional regulatory network (TRN) is used to study conditional regulatory relationships between transcriptional factors and genes. However few studies have tried to integrate genomic variation information such as copy number variation (CNV) with TRN to find causal disturbances in...

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Bibliographic Details
Main Authors: Ling Li, Baofeng Lian, Chao Li, Wei Li, Jing Li, Yuannv Zhang, Xianghuo He, Yixue Li, Lu Xie
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4045758?pdf=render