MRI-based molecular imaging of epicardium-derived stromal cells (EpiSC) by peptide-mediated active targeting

Abstract After myocardial infarction (MI), epicardial cells reactivate their embryonic program, proliferate and migrate into the damaged tissue to differentiate into fibroblasts, endothelial cells and, if adequately stimulated, to cardiomyocytes. Targeting epicardium-derived stromal cells (EpiSC) by...

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Bibliographic Details
Main Authors: Tamara Straub, Julia Nave, Pascal Bouvain, Mohammad Akbarzadeh, Siva Sai Krishna Dasa, Julia Kistner, Zhaoping Ding, Aseel Marzoq, Stefanie Stepanow, Katrin Becker, Julia Hesse, Karl Köhrer, Ulrich Flögel, Mohammad R. Ahmadian, Brent A. French, Jürgen Schrader, Sebastian Temme
Format: Article
Language:English
Published: Nature Portfolio 2020-12-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-020-78600-y