Cognitive and behavior deficits in sickle cell mice are associated with profound neuropathologic changes in hippocampus and cerebellum

Cognitive and behavior deficits in sickle cell mice are associated with profound neuropathologic changes in hippocampus and cerebellum

Strokes are perhaps the most serious complications of sickle cell disease (SCD) and by the fifth decade occur in approximately 25% of patients. While most patients do not develop strokes, mounting evidence indicates that even without brain abnormalities on imaging studies, SCD patients can present p...

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Bibliographic Details
Main Authors: Li Wang, Luis E.F. Almeida, Celia M. de Souza Batista, Alfia Khaibullina, Nuo Xu, Sarah Albani, Kira A. Guth, Ji Sung Seo, Martha Quezado, Zenaide M.N. Quezado
Format: Article
Language:English
Published: Elsevier 2016-01-01
Series:Neurobiology of Disease
Subjects:
Learning
Memory
Hippocampus
Anemia
Cerebellum
Depression
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996115300620

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http://www.sciencedirect.com/science/article/pii/S0969996115300620

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