Glypican-3 (GPC-3) Structural Analysis and Cargo in Serum Small Extracellular Vesicles of Hepatocellular Carcinoma Patients

Glypican-3 (GPC-3) Structural Analysis and Cargo in Serum Small Extracellular Vesicles of Hepatocellular Carcinoma Patients

Glypican-3 (GPC-3) is a heparin sulfate proteoglycan located extracellularly and anchored to the cell membrane of transformed hepatocytes. GPC-3 is not expressed in normal or cirrhotic liver tissue but is overexpressed in hepatocellular carcinoma (HCC). Because of this, GPC-3 is one of the most impo...

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Bibliographic Details
Main Authors: Montalbano Mauro, Perricone Ugo, Zachary Walton, Shirafkan Ali, Cristiana Rastellini, Luca Cicalese
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:International Journal of Molecular Sciences
Subjects:
hepatocellular carcinoma
Glypican-3
small extracellular vesicle
serum marker
Online Access:https://www.mdpi.com/1422-0067/24/13/10922

Internet

https://www.mdpi.com/1422-0067/24/13/10922

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