Quantitative multiplex immunohistochemistry reveals inter-patient lymphovascular and immune heterogeneity in primary cutaneous melanoma

Quantitative multiplex immunohistochemistry reveals inter-patient lymphovascular and immune heterogeneity in primary cutaneous melanoma

IntroductionQuantitative, multiplexed imaging is revealing complex spatial relationships between phenotypically diverse tumor infiltrating leukocyte populations and their prognostic implications. The underlying mechanisms and tissue structures that determine leukocyte distribution within and around...

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Bibliographic Details
Main Authors: Julia Femel, Cameron Hill, Irineu Illa Bochaca, Jamie L. Booth, Tina G. Asnaashari, Maria M. Steele, Ata S. Moshiri, Hyungrok Do, Judy Zhong, Iman Osman, Sancy A. Leachman, Takahiro Tsujikawa, Kevin P. White, Young H. Chang, Amanda W. Lund
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-02-01
Series:Frontiers in Immunology
Subjects:
melanoma
vasculature
inflammation
tertiary lymphoid structures
lymphatic vessels
metastasis, immune microenvironment
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1328602/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2024.1328602/full

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