Body mass index, smoking behavior, and depression mediated the effects of schizophrenia on chronic obstructive pulmonary disease: trans-ethnic Mendelian-randomization analysis

Body mass index, smoking behavior, and depression mediated the effects of schizophrenia on chronic obstructive pulmonary disease: trans-ethnic Mendelian-randomization analysis

BackgroundPrevious studies have highlighted the association between schizophrenia (SCZ) and chronic obstructive pulmonary disease (COPD), yet the causal relationship remains unestablished.MethodsUnder the genome-wide significance threshold (P<5×10–8), data from individuals of European (EUR) a...

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Bibliographic Details
Main Authors: Yao Ni, DaWei Zhang, Wenlong Tang, Liming Xiang, Xiaoding Cheng, Youqian Zhang, Yanyan Feng
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-05-01
Series:Frontiers in Psychiatry
Subjects:
Mendelian randomization
chronic obstructive pulmonary disease
schizophrenia
mediation analysis
causality
Online Access:https://www.frontiersin.org/articles/10.3389/fpsyt.2024.1405107/full

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https://www.frontiersin.org/articles/10.3389/fpsyt.2024.1405107/full

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