Oral Vaccination With Recombinant Pichia pastoris Expressing Iridovirus Major Capsid Protein Elicits Protective Immunity in Largemouth Bass (Micropterus salmoides)

Oral Vaccination With Recombinant Pichia pastoris Expressing Iridovirus Major Capsid Protein Elicits Protective Immunity in Largemouth Bass (Micropterus salmoides)

Largemouth bass iridovirus (LMBV) can cause high mortality and lead to heavy economic loss in the cultivation of largemouth bass, but there was no effective treatment. Here, the present study constructed a recombinant Pichia pastoris expressing LMBV major capsid protein (MCPD). The recombinant GS115...

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Bibliographic Details
Main Authors: Jia-Yun Yao, Cheng-Sai Zhang, Xue-Mei Yuan, Lei Huang, Da-Yan Hu, Zhe Yu, Wen-Lin Yin, Ling-Yun Lin, Xiao-Yi Pan, Gui-lian Yang, Chun-Feng Wang, Jin-Yu Shen, Hai-Qi Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-03-01
Series:Frontiers in Immunology
Subjects:
largemouth bass iridovirus
Pichia pastoris
immune protection
oral vaccines
presentation-related genes
immunoglobulins
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.852300/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2022.852300/full

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