Periostin Augments Vascular Smooth Muscle Cell Calcification via β-Catenin Signaling

Periostin Augments Vascular Smooth Muscle Cell Calcification via β-Catenin Signaling

Medial vascular calcification is common in chronic kidney disease (CKD) and is closely linked to hyperphosphatemia. Vascular smooth muscle cells (VSMCs) can take up pro-calcific properties and actively augment vascular calcification. Various pro-inflammatory mediators are able to promote VSMC calcif...

Full description

Bibliographic Details
Main Authors: Ioana Alesutan, Laura A. Henze, Beate Boehme, Trang T. D. Luong, Daniel Zickler, Burkert Pieske, Kai-Uwe Eckardt, Andreas Pasch, Jakob Voelkl
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Biomolecules
Subjects:
vascular calcification
vascular smooth muscle cells
phosphate
periostin
chronic kidney disease
β-catenin
Online Access:https://www.mdpi.com/2218-273X/12/8/1157

Internet

https://www.mdpi.com/2218-273X/12/8/1157

Similar Items