IFN gamma regulates proliferation and neuronal differentiation by STAT1 in adult SVZ niche

IFN gamma regulates proliferation and neuronal differentiation by STAT1 in adult SVZ niche

The adult subventricular zone (SVZ) is the main neurogenic niche in normal adult brains of mice and rats. Interferon gamma (IFNγ) has somewhat controversially been associated with SVZ progenitor proliferation and neurogenesis. The in vivo involvement of IFNγ in the physiology of the adult SVZ niche...

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Bibliographic Details
Main Authors: Leticia Pereira Gómez, Rebeca eMedina, Miguel eBaena, Anna Maria Planas, Esther ePozas
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-07-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Neurogenesis
STAT1
differentiation
SVZ
IFNγ
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncel.2015.00270/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fncel.2015.00270/full

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