Standard (8 weeks) vs long (12 weeks) timing to minimally-invasive surgery after NeoAdjuvant Chemoradiotherapy for rectal cancer: a multicenter randomized controlled parallel group trial (TiMiSNAR)

Abstract Background The optimal timing of surgery in relation to chemoradiation is still controversial. Retrospective analysis has demonstrated in the recent decades that the regression of adenocarcinoma can be slow and not complete until after several months. More recently, increasing pathologic Co...

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Main Authors: Igor Monsellato, Filippo Alongi, Elisa Bertocchi, Stefania Gori, Giacomo Ruffo, Elisa Cassinotti, Ludovica Baldarti, Luigi Boni, Graziano Pernazza, Fabio Pulighe, Carlo De Nisco, Roberto Perinotti, Emilio Morpurgo, Tania Contardo, Enzo Mammano, Ugo Elmore, Roberto Delpini, Riccardo Rosati, Federico Perna, Andrea Coratti, Benedetta Menegatti, Sergio Gentilli, Paolo Baroffio, Piero Buccianti, Riccardo Balestri, Cristina Ceccarelli, Valter Torri, Davide Cavaliere, Leonardo Solaini, Giorgio Ercolani, Elena Traverso, Vittorio Fusco, Maura Rossi, Fabio Priora, G. Numico, Paola Franzone, Sara Orecchia
Format: Article
Language:English
Published: BMC 2019-12-01
Series:BMC Cancer
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Online Access:https://doi.org/10.1186/s12885-019-6271-3