The Beneficial Effect of Praeruptorin C on Osteoporotic Bone in Ovariectomized Mice via Suppression of Osteoclast Formation and Bone Resorption

The Beneficial Effect of Praeruptorin C on Osteoporotic Bone in Ovariectomized Mice via Suppression of Osteoclast Formation and Bone Resorption

Being a highly prevalent disease, osteoporosis causes metabolism defects. Low bone density, compromised bone strength, and an increased danger of fragility fracture are its main characteristics. Natural compounds have been considered as potential alternative therapeutic agents for treating osteoporo...

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Bibliographic Details
Main Authors: Xuqiang Liu, Jie-Fen Chin, Xinhua Qu, Haidi Bi, Yuan Liu, Ziqiang Yu, Zanjing Zhai, An Qin, Bin Zhang, Min Dai
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-09-01
Series:Frontiers in Pharmacology
Subjects:
praeruptorin C
osteoclast
ovariectomized mice
osteoporosis
NF-κB
c-Jun N-terminal kinase
Online Access:http://journal.frontiersin.org/article/10.3389/fphar.2017.00627/full

Internet

http://journal.frontiersin.org/article/10.3389/fphar.2017.00627/full

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