Cell‐to‐cell variability of alternative RNA splicing
Abstract Heterogeneity in the expression levels of mammalian genes is large even in clonal populations and has phenotypic consequences. Alternative splicing is a fundamental aspect of gene expression, yet its contribution to heterogeneity is unknown. Here, we use single‐molecule imaging to character...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Springer Nature
2011-07-01
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Series: | Molecular Systems Biology |
Subjects: | |
Online Access: | https://doi.org/10.1038/msb.2011.32 |