Application of bacteriophage φPaP11-13 attenuates rat Cutibacterium acnes infection lesions by promoting keratinocytes apoptosis via inhibiting PI3K/Akt pathway

Application of bacteriophage φPaP11-13 attenuates rat Cutibacterium acnes infection lesions by promoting keratinocytes apoptosis via inhibiting PI3K/Akt pathway

ABSTRACTAcne vulgaris caused by antibiotic-resistant Cutibacterium acnes (C. acnes) infection is difficult to treat conventionally. Phages have been suggested as a potential solution, but research on the mechanism of phage treatment is inadequate. This research investigates the underlying molecular...

Full description

Bibliographic Details
Main Authors: Yuanyuan Liu, Ni Zhen, Danxi Liao, Jiahui Niu, Ruolan Liu, Zijiao Li, Zeyuan Lei, Zichen Yang
Format: Article
Language:English
Published: American Society for Microbiology 2024-02-01
Series:Microbiology Spectrum
Subjects:
Cutibacterium acnes
acne vulgaris
phage
apoptosis
PI3K/Akt
Propionibacterium acnes
Online Access:https://journals.asm.org/doi/10.1128/spectrum.02838-23

Internet

https://journals.asm.org/doi/10.1128/spectrum.02838-23

Similar Items