Impaired Repopulating Ability of <i>Uhrf2</i><sup>−/−</sup> Hematopoietic Progenitor Cells in Mice

Impaired Repopulating Ability of <i>Uhrf2</i><sup>−/−</sup> Hematopoietic Progenitor Cells in Mice

UHRF proteins catalyze the ubiquitination of target proteins and are involved in regulating gene expression. Some studies reported a reduced expression of UHRF2 in acute leukemia cells, but the role of UHRF2 in hematopoiesis remains unknown. Here, we generated <i>Uhrf2<sup>−/−</sup>...

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Bibliographic Details
Main Authors: Takahiro Sano, Koki Ueda, Keiji Minakawa, Tsutomu Mori, Yuko Hashimoto, Haruhiko Koseki, Yasuchika Takeishi, Kazuhiko Ikeda, Takayuki Ikezoe
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:Genes
Subjects:
<i>UHRF2</i>
hematopoietic stem and progenitor cells
hematopoiesis
Online Access:https://www.mdpi.com/2073-4425/14/8/1531

Internet

https://www.mdpi.com/2073-4425/14/8/1531

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