Structural basis of thiamine transport and drug recognition by SLC19A3
Abstract Thiamine (vitamin B1) functions as an essential coenzyme in cells. Humans and other mammals cannot synthesise this vitamin de novo and thus have to take it up from their diet. Eventually, every cell needs to import thiamine across its plasma membrane, which is mainly mediated by the two spe...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2024-10-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-024-52872-8 |